Ro 20-1724
CAS No. 29925-17-5
Ro 20-1724 ( Ro20-1724; Ro 20-1724; Ro-20-1724; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone )
产品货号. M27133 CAS No. 29925-17-5
Ro20-1724 is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥437 | 有现货 |
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10MG | ¥672 | 有现货 |
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25MG | ¥1109 | 有现货 |
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50MG | ¥1702 | 有现货 |
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100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Ro 20-1724
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Ro20-1724 is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM.
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产品描述Ro20-1724 is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM.(In Vivo):RO-20-1724 was found to not only improve learning and memory in MWM and PA paradigms but also restore STZ induced elevation in cholinesterase activity. Further, RO-20-1724 significantly reduced malondialdehyde and nitrite levels, and restored the glutathione levels indicating attenuation of oxidative stress.
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同义词Ro20-1724; Ro 20-1724; Ro-20-1724; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone
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通路Angiogenesis
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靶点PDE
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受体IL-8; NOD2
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研究领域——
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适应症——
化学信息
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CAS Number29925-17-5
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分子量278.4
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分子式C15H22N2O3
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纯度>98% (HPLC)
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溶解度——
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SMILESCCCCOc1cc(CC2CNC(=O)N2)ccc1OC
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Rickard DJ, et al. Identification of benzimidazole diamides as selective inhibitors of the nucleotide-binding oligomerization domain 2 (NOD2) signaling pathway. PLoS One. 2013;8(8):e69619. Published 2013 Aug 1.
产品手册
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