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Ro 20-1724

CAS No. 29925-17-5

Ro 20-1724 ( Ro20-1724; Ro 20-1724; Ro-20-1724; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone )

产品货号. M27133 CAS No. 29925-17-5

Ro20-1724 is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥437 有现货
10MG ¥672 有现货
25MG ¥1109 有现货
50MG ¥1702 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Ro 20-1724
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Ro20-1724 is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM.
  • 产品描述
    Ro20-1724 is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM.(In Vivo):RO-20-1724 was found to not only improve learning and memory in MWM and PA paradigms but also restore STZ induced elevation in cholinesterase activity. Further, RO-20-1724 significantly reduced malondialdehyde and nitrite levels, and restored the glutathione levels indicating attenuation of oxidative stress.
  • 同义词
    Ro20-1724; Ro 20-1724; Ro-20-1724; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone
  • 通路
    Angiogenesis
  • 靶点
    PDE
  • 受体
    IL-8; NOD2
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    29925-17-5
  • 分子量
    278.4
  • 分子式
    C15H22N2O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    CCCCOc1cc(CC2CNC(=O)N2)ccc1OC
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Rickard DJ, et al. Identification of benzimidazole diamides as selective inhibitors of the nucleotide-binding oligomerization domain 2 (NOD2) signaling pathway. PLoS One. 2013;8(8):e69619. Published 2013 Aug 1.
产品手册
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